COMPARE Project

From the COMPARE website:

Outcome switching in clinical trials is a serious problem. We are systematically checking every trial published in the top five medical journals, to see if they have misreported their findings.

First, we compare each clinical trial report against its registry entry. Some trials report their outcomes perfectly. For the others, we count how many of the outcomes specified in the registry were never reported. And we count how many outcomes were silently added.

Second, whenever we detect unreported or added outcomes, we write a letter to the journal pointing them out, so that readers are aware of the problems. We are tracking which journals have published our letters after 4 weeks - and which haven't.